Home

People

Cytosim

Publications

Misc

• Regulation of microtubule dynamics by reaction cascades around chromosomes.
  Chaitanya Athale, Ana Dinarina, Maria Mora Corral, Celine Pugieux, Francois Nedelec and Eric Karsenti
  Science vol. 322 no. 5905, 1243-1247; November 21 2008





• Mechanism of phototaxis in marine zooplankton.
  Gaspar Jekely, Julien Colombelli, Harald Hausen, Keren Guy, Ernst Stelzer, Francois Nedelec and Detlev Arendt
  Nature vol. 456, 395-399; November 20 2008
  Simulations
  




• Force and Length-dependent catastrophe activities explain interphase microtubule organization in fission yeast.
  Dietrich Foethke, Tatyana Makushok, Damian Brunner and Francois Nedelec
  preprint August 2008



• Spatial regulation improves antiparallel microtubule overlap during mitotic spindle assembly
  Wilbur Channels, Francois Nedelec, Yixian Zheng and Pablo Iglesias
  Biophysical Journal; Dec. 2007


• Collective Langevin Dynamics of Flexible Cytoskeletal Fibers
  Francois Nedelec and Dietrich Foethke
  New Journal of Physics; vol 9 (11) pp 427-; November 2007
  Download and run the simulation demo live:
  For mac OSX (disk-image, 1MB), for windows (zip file 4MB)
  This article describes the mathematical foundations of cytosim
  


• Cortical Microtubule Contacts Position the Spindle in C. elegans Embryos
  Cleopatra Kozlowski, Martin Srayko, and Francois Nedelec
  Cell 129; 499-510; May 2007
  Download and run the simulation live!
  Mac OSX (disk-image, 34 MB)
  Supplementary data
  


• Crosslinkers and Motors Organize Dynamic Microtubules to Form Stable Bipolar Arrays in Fission Yeast
  Marcel Janson, Rose Loughlin, Isabelle Loiodice, Chuanhai Fu, Damian Brunner, Francois Nedelec and Phong Tran
  Cell 128; 357-68; Jan 2007
  Download and run the simulation live!
  Mac OSX (zip file with disk-image, 9 MB)
  Windows (zip file, 23 MB)
  Simulation movies
  



---



• Modelling microtubules patterns
  (review)
  Eric Karsenti, Francois Nedelec and Thomas Surrey
  Nature Cell Biology 8(11); 1204-11; November 2006
  
  
• Mechanisms for focusing mitotic spindle poles by minus end-directed motor proteins
  Gohta Goshima, Francois Nedelec and Ronald D. Vale
  Journal of Cell Biology 171;229-240; 2005.
  Download and run the simulation live!
  Mac OSX (disk-image, 1.4 MB)
  Windows (tar file, 9 MB)
  
  
  
• The Mitotic Spindle and Actin Tails
  (review)
  Eric Karsent and Francois Nedelec
  Biology of the Cell 96(3): 237-40; 2004.
  PS: Our citation might be missleading: we cite more recent work, but thermal ratchets for actin polymerization were introduced by Mogilner and Oster (Biophysical J. 1996, Dec; 71(6):3030-45).
  
  
• Self-Organisation and Forces in the Microtubule Cytoskeleton
  (review)
  Francois Nedelec, Thomas Surrey and Eric Karsenti
  Current Opinion in Cell Biology 15(1): 118-24; 2003.
  
  
• Computer Simulations Reveal Motor Properties Generating Stable Anti-Parallel Microtubule Interactions,
  Francois Nedelec,
  Journal of Cell Biology 158(6): 1005-1015; 2002.
  Supplementary material
  
  
  
• Dynamics of Microtubule Aster Formation by Motor Complexes,
  Francois Nedelec and Thomas Surrey,
  C. R. Acad. Sci. Paris, t.2 Serie iv: 841-847; 2001.
  
  
• Physical Properties Determining Self-Organization of Motors and Microtubules,
  Thomas Surrey, Francois Nedelec, Stanislas Leibler and Eric Karsenti,
  Science 292: 1167-1171; 2001.
  Supplementary material
  
  
• Dynamic Concentration of Motors in Microtubule Arrays,
  Francois Nedelec, Thomas Surrey and A.C. Maggs,
  Phys. Rev. Lett. 86: 3192-3195; 2001.
  
  
• De l'Action Collective des Motors a l'Ordre Cellulaire,
  (review in french)
  Francois Nedelec et Thomas Surrey,
  Medecine/Sciences 16: 739-744; 2000.
  
  
• Assaying Spatial Organization of Microtubules by Kinesin Motors,
  Francois Nedelec and Thomas Surrey,
  Kinesin Protocols, Methods in Molecular Biology 164: 213-222; 2000.
  
  
• Chromophore-Assisted Light Inactivation and Self-Organization of Microtubules and Motors,
  Thomas Surrey, Michael Elowitz, Pierre-Etienne Wolf, Feng Yang, Francois Nedelec, Kevin Shokat and Stanislas Leibler,
  Proc. Nat. Acad. Sci. USA, 95: 4293-4298; 1998.
  
  
• Self-Organization of Microtubules and Motors,
  Francois Nedelec, Thomas Surrey, A.C. Maggs, Stanislas Leibler,
  Nature 389: 305-308; 1997.
  More images and movies
  
  
  
  
• Auto-organisation d'un Melange de Microtubules et de Moteurs,
  Francois Nedelec, Thesis Dissertation, Orsay University; 1998.
  Beyond the abstract, this is entirely written in French.

The material available here is copyrighted. Please, refer to and follow the appropriate journal policy. Copies of the articles can usually be downloaded and printed only for the reader's personal research or study. For any other use, please contact the publisher directly.