þÿ<html> <head> <title>Spindle Positioning in C.elegans: Phenotype Gallery</title> <META NAME="description" CONTENT="Spindle Positioning in C.elegans: Phenotype Gallery"> <META NAME="keywords" CONTENT="Spindle Positioning in C.elegans Phenotype Gallery"> </head> <body bgcolor="#CCFFCC"> <h2 align="center"> Cortical Microtubule Contacts<br> Position the Spindle<br> in C. elegans embryos<br> <FONT SIZE=6>Phenotype Gallery</FONT><br> </h2> <A HREF="movies.html"><BR>To supplementary movies</A><br> <a href="..">Back</a> <h2> Phenotype Gallery:<br> </h2> <br><br> <table border="1"> <tr> <td><p><B>Parameter Name</B></p></td> <td><p><B>Value in Reference Simulation</B></p></td> <td><p><B>Parameter is decreased</B></p></td> <td><p><B>Parameter is increased</B></p></td> </tr> <tr> <td><p>Microtubule Growth Speed </p></td> <td><a href="phenotypes/wt.mov">0.51µm/s </a> </td> <td><a href="phenotypes/grow=0.3104.mov">0.3104µm/s </a></td> <td><a href="phenotypes/grow=2.785.mov">2.785 µm/s </a></td> </tr> <tr> <td><p>Microtubule Shrink Speed </p></td> <td><a href="phenotypes/wt.mov">0.84µm/s </a> </td> <td><a href="phenotypes/mtdynspeed1=-0.133.mov">0.133µm/s </a></td> <td><a href="phenotypes/mtdynspeed1=-3.612.mov">3.612 µm/s </a></td> </tr> <tr> <td><p>Microtubule Catastrophe Rate </p></td> <td><a href="phenotypes/wt.mov">5/s </a> </td> <td><a href="phenotypes/mtdyntrans2=0.722.mov">0.722/s </a></td> <td><a href="phenotypes/mtdyntrans2=9.487.mov">9.487/s </a></td> </tr> <tr> <td><p>Fiber (group of microtubules) Rigidity </p></td> <td><a href="phenotypes/wt.mov">120 pN/µm2 </a> </td> <td><a href="phenotypes/mtrigid=70.000.mov">70.0 pN/µm2 </a></td> <td><a href="phenotypes/mtrigid=899.100.mov">899.1 pN/µm2 </a></td> </tr> <tr> <td><p>Force Generator Attachment Rate </p></td> <td><a href="phenotypes/wt.mov">5/s </a> </td> <td><a href="phenotypes/haattachrate=1.034.mov">1.034/s </a></td> <td><a href="phenotypes/haattachrate=9.202.mov">9.202/s </a></td> </tr> <tr> <td><p>Force Generator Detachment Rate </p></td> <td><a href="phenotypes/wt.mov">0.003/s </a> </td> <td><a href="phenotypes/haenddetachrate=0.001.mov">0.001/s </a></td> <td><a href="phenotypes/haenddetachrate=0.032.mov">0.032/s </a></td> </tr> <tr> <td><p>Force Generator / Cortex Combined Elasticity </p></td> <td><a href="phenotypes/wt.mov">370pN/µm </a> </td> <td><a href="phenotypes/km=51.000.mov">51.0 pN/µm </a></td> <td><a href="phenotypes/km=900.600.mov">900.6 pN/µm </a></td> </tr> <tr> <td><p>Force Generator Characteristic Force </p></td> <td><a href="phenotypes/wt.mov">28 pN </a> </td> <td><a href="phenotypes/haforce=10.490.mov">10.490 pN </a></td> <td><a href="phenotypes/haforce=92.520.mov">92.520 pN </a></td> </tr> <tr> <td><p>Asymmetry (Softness of posterior cortex compared to anterior) </p></td> <td><a href="phenotypes/wt.mov">posterior is 50% softer </a> </td> <td><a href="phenotypes/asymmetry=0.925.mov">7% </a></td> <td><a href="phenotypes/asymmetry=0.196.mov">80% </a></td> </tr> <tr> <td><p>Viscosity </p></td> <td><a href="phenotypes/wt.mov">1.0 pNs/µm2 </a> </td> <td><a href="phenotypes/visc=0.124.mov">0.124 pNs/µm2 </a></td> <td><a href="phenotypes/visc=1.917.mov">1.917 pNs/µm2 </a></td> </tr> </table> <BR> </body> </html>