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Our long-term research objective is to understand microtubule organization in living cells, with an emphasis on mitosis. We develop in-vitro assays, quantitative image analysis and cytosim, a computer simulation to study cellular architecture from a mechanistic perspective, modeling the interactions of microtubules and associated proteins such as molecular motors.
In the past, we combined simulations and experiments to study microtubule self-organization, and the mechanical stability of two interacting asters. More recently, we looked at the focusing of mitotic fibers, the formation of antiparallel arrays of microtubules in fission yeast and the spindle positionning in C. elegans.
We are supported by BioMS, an initiative in Systems Biology, and involved in Cell networks.
Postdoctoral Opportunity:
We are seeking highly motivated candidates with a recent PhD. Experience in computational biology or theoretical physics would be particularly welcomed. The candidate does not need to have prior knowledge in Biology, but a strong desire to learn is essential. Good programming and mathematical skills are necessary.
If you are interested, please contact us with a CV and motivation letter.
PhD Opportunity:
We offer a PhD project in collaboration with Elmar Schiebel and Thomas Surrey
This is a position from the University of Heidelberg. If you are interested, please apply online.
Contact: Francois Nedelec
Cell Biology and Biophysics
EMBL Heidelberg
Telephone/Email