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Cellular architecture group at EMBL

Our group on www.embl.de

Our long-term research objective is to understand microtubule organization in living cells, with an emphasis on mitosis. We develop in-vitro assays, quantitative image analysis and cytosim, a computer simulation to study cellular architecture from a mechanistic perspective, modeling the interactions of microtubules and associated proteins such as molecular motors.
In the past, we combined simulations and experiments to study microtubule self-organization, and the stability of two interacting asters. We also studied the focusing of mitotic fibers, the formation of antiparallel arrays of microtubules in fission yeast and the spindle positionning in C. elegans. Please see our publication list for references.

New: a model of microtubule organization in the meiotic spindle:
Simulated Spindle


We are supported by BioMS, an initiative in Systems Biology, and involved in Cell networks.

Postdoctoral opportunity:
We are seeking highly motivated candidates with a recent PhD. Experience in mathematics, computation and/or physics are highly valued. The candidate does not need to have prior knowledge in Biology, but a strong interest in this field is essential. If you are interested, please contact us with a CV and motivation letter.

PhD opportunity:
If you are interested in doing your PhD work with us, please check the EMBL PhD program.


Contact: Francois Nedelec
Cell Biology and Biophysics
EMBL Heidelberg
Contact